Blood Lead Levels and Disturbances of Liver Function of Pregnant Woman In Grinting Bulakamba Sub District Brebes District.
Keywords:
Blood Lead Level, Pregnant Women, Disturbances Of Liver FunctionAbstract
Lead is a highly toxic metal and can affect every organ and system in the human body. The tugs that enter into the body will be distributed into the blood and 95% of lead in the blood is bound by red blood cells only 5% in the blood plasma. The use of lead in large or repeated quantities and will be stored cumulatively on the liver. This is because About 90% of lead gets into the blood circulation, 25% is deposited in the liver. The result of the research on the workers in lead smelting was found there is significant correlation of Pb level in blood with the disruption of liver function. The purpose of the research wanted to know the disruption of liver function and analyze the blood lead level in pregnant women group in Grinting, Bulakamba Sub-district of Brebes district. This research uses observational analytic method with cross-sectional design with 49 respondents. The test result showed that all respondents had lead level (Pb) above NAB 5 μg / dL with mean ± SD: 19,74 ± 9,214, median 19,70, minimum 6,33 and maximum 36,60. Although all respondents with Pb levels exceeded NAB but SGOT levels and SGPT levels pregnant women in agricultural areas showed normal results. By using cut off point median value (19,70) respondents with Lead (Pb) level in "high blood" equal to (51%). The results of the correlation test and test of different levels of lead (Pb) "high" and "low" on SGOT and SGPT levels showed no significant relationship. all respondents had Pb levels exceeding NAB 5 μg / dLL; there was no relationship and difference between lead level (Pb) in blood with examination of SGOT and SGPT levels.
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