Analyzing Research Trends in Microplastic Toxicity: A Comprehensive Bibliometric Review
Keywords:
Microplastics, Toxicity, Bibliometric Analysis, Environmental PollutionAbstract
Microplastics (MPs) are pervasive environmental contaminants that pose significant risks to ecosystems and human health. The study of microplastic toxicity has gained considerable attention over the past decade, with a growing body of research exploring their distribution, toxicological effects, and interactions with other pollutants. The primary objective of this bibliometric study is to identify and analyze research trends in microplastic toxicity from 2012 to 2025 using Scopus data. This analysis aims to provide insights into the evolution of research focus, key contributors, and emerging themes in this critical area of environmental science. A comprehensive bibliometric analysis was conducted using Scopus database data covering publications from 2012 to 2025. Tools such as VOSviewer were employed for performance evaluation and science mapping. The analysis of 5563 publications revealed a significant upward trend in annual research output on microplastic toxicity. There has been a notable increase in publications on microplastic toxicity, reflecting heightened scientific interest and awareness. China emerged as a leading contributor to this research area, followed by the United States and India. Early research primarily focused on identifying and distributing microplastics, while recent studies have shifted towards understanding their toxicological effects, including oxidative stress, apoptosis, and interactions with other pollutants. Science of the Total Environment and Journal of Hazardous Materials were identified as the most productive journals in this field, publishing a significant proportion of relevant articles.
References
Abad López, A. P., Trilleras, J., Arana, V. A., Garcia-Alzate, L. S., & Grande-Tovar, C. D. (2023). Atmospheric microplastics: exposure, toxicity, and detrimental health effects. RSC Advances, 13(11), 7468–7489. https://doi.org/10.1039/d2ra07098g
Anbumani, S., & Kakkar, P. (2018). Ecotoxicological effects of microplastics on biota: a review. Environmental Science and Pollution Research, 25(15), 14373–14396. https://doi.org/10.1007/s11356-018-1999-x
Ashokkumar, V., Chandramughi, V. P., Mohanty, K., & Gummadi, S. N. (2025). Microplastic pollution: Critical analysis of global hotspots and their impact on health and ecosystems. Journal of Environmental Management, 381(October 2024), 124995. https://doi.org/10.1016/j.jenvman.2025.124995
Aunno, T. D. (2016). primary care workforce capacity. 00(0), 1–10. https://doi.org/10.1097/HMR.0000000000000094
Cao, Y., Ma, Y., Han, Y., Bian, J., Yu, X., Wang, Z., Liu, J., Feng, W., Deng, Y., & Miao, Q. (2024). Effect and environmental behaviour of microplastics in soil. Waste Management and Research, 42(7), 511–519. https://doi.org/10.1177/0734242X231190811
Chen, J., Guo, C., Xuan, Y., & Ding, T. (2023). Analysis and toxicity of microplastics in organisms and humans originated from aquatic environment. TrAC - Trends in Analytical Chemistry, 168(August), 117293. https://doi.org/10.1016/j.trac.2023.117293
Du, Z., Yu, X., Li, X., Zhang, L., Lin, Y., He, Y., Wu, Y., Baspakova, A., Afashar, A., Suleimenova, R., Berdygaliev, A. B., Ramankulova, A., Kandygulova, G. J., Mussin, N. M., Mahdipour, M., Zhilisbayeva, K. R., Tanideh, N., Tamadon, A., Li, M., … Sharma, S. (2024). Examining the Presence of Microplastics in Wastewater: A Bibliometric Analysis and Overview. Fate of Microplastics in Wastewater Treatment Plants: Occurrence, Identification, Potential Factors, and Future Perspectives, 139(5), 1–16. https://doi.org/10.1201/9781003438793-1
Hazarika, R., & Sudhier, K. G. (2024). Scientometric Analysis and Visualization of Research on the Effects of Microplastics on Marine Life. Journal of Scientometric Research, 13(2), 485–495. https://doi.org/10.5530/jscires.13.2.39
Ho, C. M., Feng, W., Li, X., Ngien, S. K., Yu, X., Song, F., Yang, F., & Liao, H. (2025). Microplastic distribution and its implications for human health through marine environments. Journal of Environmental Management, 382(April), 125427. https://doi.org/10.1016/j.jenvman.2025.125427
Jeong, J., & Choi, J. (2019). Adverse outcome pathways potentially related to hazard identification of microplastics based on toxicity mechanisms. Chemosphere, 231, 249–255. https://doi.org/10.1016/j.chemosphere.2019.05.003
Liu, W., Zeng, M., Li, Y., Chen, G., Wen, J., & Wang, J. (2024). Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends. TrAC - Trends in Analytical Chemistry, 172(January). https://doi.org/10.1016/j.trac.2024.117608
Luo, W. Q., Cao, M. T., Sun, C. X., Wang, J. J., Gao, M. X., He, X. R., Dang, L. N., Geng, Y. Y., Li, B. Y., Li, J., Shi, Z. C., & Yan, X. R. (2025). Size-dependent internalization of polystyrene microplastics as a key factor in macrophages and systemic toxicity. Journal of Hazardous Materials, 490(October 2024), 137701. https://doi.org/10.1016/j.jhazmat.2025.137701
Mishra, M., Sudarsan, D., Santos, C. A. G., da Silva, R. M., Beja, S. K., Paul, S., Bhanja, P., & Sethy, M. (2024). Current patterns and trends of microplastic pollution in the marine environment: A bibliometric analysis. Environmental Science and Pollution Research, 31(15), 22925–22944. https://doi.org/10.1007/s11356-024-32511-x
Nguyen, M. K., Lin, C., & Nguyen, D. D. (2025). Microplastic pollution associated with probabilistic human health risks: Potential hazards, critical factors, challenges, and limitations. Marine Pollution Bulletin, 221(June), 118528. https://doi.org/10.1016/j.marpolbul.2025.118528
Pal, D., Prabhakar, R., Barua, V. B., Zekker, I., Burlakovs, J., Krauklis, A., Hogland, W., & Vincevica-Gaile, Z. (2025). Microplastics in aquatic systems: A comprehensive review of its distribution, environmental interactions, and health risks. In Environmental Science and Pollution Research (Vol. 32, Issue 1). Springer Berlin Heidelberg. https://doi.org/10.1007/s11356-024-35741-1
Pei, D.-S., & Yoganandham, S. T. (2023). Molecular Toxicity Mechanism of Microplastics in the Reservoir. In Reservoir Ecotoxicology (pp. 173–181). Springer International Publishing. https://doi.org/10.1007/978-3-031-26344-6_15
Pei, J., Qu, M., Sun, L., Wang, X., & Yin, Y. (2024). The relationship between indoor air quality (IAQ) and perceived air quality (PAQ) – a review and case analysis of Chinese residential environment. Energy and Built Environment, 5(2), 230–243. https://doi.org/10.1016/j.enbenv.2022.09.005
Periyasamy, A. P. (2025). Functionalized textile microplastics: A closer look at the issues, strategy, and legislation on the microplastic reduction. Kuwait Journal of Science, 52(3), 100395. https://doi.org/10.1016/j.kjs.2025.100395
Rakib, M. R. J., Sarker, A., Ram, K., Uddin, M. G., Walker, T. R., Chowdhury, T., Uddin, J., Khandaker, M. U., Rahman, M. M., & Idris, A. M. (2023). Microplastic Toxicity in Aquatic Organisms and Aquatic Ecosystems: a Review. Water, Air, and Soil Pollution, 234(1). https://doi.org/10.1007/s11270-023-06062-9
Srinivas, G., & Rajesh, K. (2025). Ecological impact of microplastic pollution on marine food webs. International Journal of Aquatic Research and Environmental Studies, 5(1), 390–407. https://doi.org/10.70102/IJARES/V5I1/5-1-37
Thornton Hampton, L. M., Bouwmeester, H., Brander, S. M., Coffin, S., Cole, M., Hermabessiere, L., Mehinto, A. C., Miller, E., Rochman, C. M., & Weisberg, S. B. (2022). Research recommendations to better understand the potential health impacts of microplastics to humans and aquatic ecosystems. Microplastics and Nanoplastics, 2(1). https://doi.org/10.1186/s43591-022-00038-y
Wang, Y., Liu, G., Wang, Y., Mu, H., Shi, X., Wang, C., & Wu, N. (2023). The Global Trend of Microplastic Research in Freshwater Ecosystems. Toxics, 11(6), 1–13. https://doi.org/10.3390/toxics11060539
Xing, Z., Fu, W., Li, L., & Wu, S. (2025). Bibliometric analysis of microplastics research: Advances and future directions (2020–2024). Continental Shelf Research, 285(November 2024), 105371. https://doi.org/10.1016/j.csr.2024.105371
Yang, Y., Chen, Y., Gao, Y., Jin, Y., & Xu, F. (2025). Mapping research frontiers in microplastics-induced oxidative stress: a bibliometric analysis (2010–2024). Frontiers in Environmental Science, 13(April), 1–5. https://doi.org/10.3389/fenvs.2025.1555341
Yildirim, G., Anindita, M., Pan, X., Rahman, S., Alim, M. A., Shaik, R., & Rahman, A. (2024). Bibliometric Insights into Microplastic Pollution in Freshwater Ecosystems. Water (Switzerland), 16(22). https://doi.org/10.3390/w16223237